Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection

Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection

ABSTRACT In this study, we examined the relationships between anti-influenza virus serum antibody titers, clinical disease, and peripheral blood leukocyte (PBL) global gene expression during presymptomatic, acute, and convalescent illness in 83 participants infected with 2009 pandemic H1N1 virus in...

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Bibliographic Details
Main Authors: Kathie-Anne Walters, Ruoqing Zhu, Michael Welge, Kelsey Scherler, Jae-Keun Park, Zainab Rahil, Hao Wang, Loretta Auvil, Colleen Bushell, Min Young Lee, David Baxter, Tyler Bristol, Luz Angela Rosas, Adriana Cervantes-Medina, Lindsay Czajkowski, Alison Han, Matthew J. Memoli, Jeffery K. Taubenberger, John C. Kash
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
HA head antibodies
HA stalk antibodies
NA antibodies
antibody function
genomics
host response
Online Access:https://journals.asm.org/doi/10.1128/mBio.00760-19

Internet

https://journals.asm.org/doi/10.1128/mBio.00760-19

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