Dexmedetomidine did not reduce the effects of tourniquet-induced ischemia-reperfusion injury during general anesthesia

Dexmedetomidine did not reduce the effects of tourniquet-induced ischemia-reperfusion injury during general anesthesia

Ischemia reperfusion injury causes the release of free oxygen radicals. Free oxygen radicals initiate the production of toxic metabolites, such as malondialdehyde (MDA), through the lipid peroxidation of cellular membranes. Following lipid peroxidation, the antioxidant enzyme system is activated aga...

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Bibliographic Details
Main Authors: Evrim Bostankolu, Hilal Ayoglu, Serhan Yurtlu, Rahsan Dilek Okyay, Gülay Erdogan, Yeliz Deniz, Volkan Hanci, Murat Can, Isil Ozkocak Turan
Format: Article
Language:English
Published: Wiley 2013-02-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Dexmedetomidine
Ischemia reperfusion injury
Malondialdehyde
Total antioxidant capacity
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X12002148

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http://www.sciencedirect.com/science/article/pii/S1607551X12002148

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