No Isolate, No Problem: Using a Novel Insertion Sequence PCR to Link Rats to Human Shigellosis Cases in an Underserved Urban Community

No Isolate, No Problem: Using a Novel Insertion Sequence PCR to Link Rats to Human Shigellosis Cases in an Underserved Urban Community

ABSTRACT During an investigation into a cluster of Shigella flexneri serotype 2a cases in an underserved community, we assessed the relatedness of human and rat S. flexneri isolates utilizing a novel PCR targeting insertion sites (IS-PCR) of mobile elements in the Shigella genome characteristic of t...

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Bibliographic Details
Main Authors: Gordon Ritchie, Victor Leung, Chelsea G. Himsworth, Kaylee A. Byers, Lisa K. F. Lee, Samuel D. Chorlton, Aleksandra Stefanovic, Marc G. Romney, Nancy Matic, Christopher F. Lowe
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
Rattus norvegicus
Shigella flexneri
insertion sequence
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04777-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04777-22

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