On the Impact of the Pangenome and Annotation Discrepancies While Building Protein Sequence Databases for Bacteria Proteogenomics

On the Impact of the Pangenome and Annotation Discrepancies While Building Protein Sequence Databases for Bacteria Proteogenomics

In proteomics, peptide information within mass spectrometry (MS) data from a specific organism sample is routinely matched against a protein sequence database that best represent such organism. However, if the species/strain in the sample is unknown or genetically poorly characterized, it becomes ch...

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Bibliographic Details
Main Authors: Karla C. T. Machado, Suereta Fortuin, Gisele Guicardi Tomazella, Andre F. Fonseca, Robin Mark Warren, Harald G. Wiker, Sandro Jose de Souza, Gustavo Antonio de Souza
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Microbiology
Subjects:
databases
proteomics
proteogenomics
mass spectrometry
pangenome
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01410/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01410/full

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