The association between osteopontin gene polymorphisms, osteopontin expression and sarcoidosis.

BACKGROUND:Sarcoidosis is a systemic inflammatory disease of unknown etiology. Osteopontin (SPP1, OPN) is an extra cellular matrix glycoprotein and cytokine with a known role in granuloma formation and in autoimmune and inflammatory diseases. OBJECTIVE:To determine whether plasma OPN levels are elev...

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Bibliographic Details
Main Authors: Hadas Lavi, Miri Assayag, Assaf Schwartz, Nissim Arish, Zvi G Fridlender, Neville Berkman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333822?pdf=render