PARP1 Regulates Circular RNA Biogenesis though Control of Transcriptional Dynamics

PARP1 Regulates Circular RNA Biogenesis though Control of Transcriptional Dynamics

Circular RNAs (circRNAs) are a recently discovered class of RNAs derived from protein-coding genes that have important biological and pathological roles. They are formed through backsplicing during co-transcriptional alternative splicing; however, the unified mechanism that accounts for backsplicing...

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Bibliographic Details
Main Authors: Rebekah Eleazer, Kalpani De Silva, Kalina Andreeva, Zoe Jenkins, Nour Osmani, Eric C. Rouchka, Yvonne Fondufe-Mittendorf
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
circRNAs
transcription elongation
poly (ADP-ribose) polymerase
splicing
backsplicing
gene architecture
Online Access:https://www.mdpi.com/2073-4409/12/8/1160

Internet

https://www.mdpi.com/2073-4409/12/8/1160

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