Label-free nonlinear optical signatures of extracellular vesicles in liquid and tissue biopsies of human breast cancer

Abstract Extracellular vesicles (EVs) have been implicated in metastasis and proposed as cancer biomarkers. However, heterogeneity and small size makes assessments of EVs challenging. Often, EVs are isolated from biofluids, losing spatial and temporal context and thus lacking the ability to access E...

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Bibliographic Details
Main Authors: Janet E. Sorrells, Jaena Park, Edita Aksamitiene, Marina Marjanovic, Elisabeth M. Martin, Eric J. Chaney, Anna M. Higham, Kimberly A. Cradock, Zheng G. Liu, Stephen A. Boppart
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-55781-4