Improved mitochondrial function in brain aging and Alzheimer disease - the new mechanism of action of the old metabolic enhancer piracetam

Piracetam, the prototype of the so-called nootropic drugs’ is used since many years in different countries to treat cognitive impairment in aging and dementia. Findings that piracetam enhances fluidity of brain mitochondrial membranes led to the hypothesis that piracetam might improve mito...

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Bibliographic Details
Main Authors: Kristina Leuner, Christopher Kurz, Giorgio Guidetti, Jean-Marc Orgogozo, Walter E Müller
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2010.00044/full