Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease
The risk and progression of pulmonary vascular disease in patients with congenital heart disease is dependent on the hemodynamics associated with different lesions. However, the underlying mechanisms are not understood. Endothelin-1 is a potent vasoconstrictor that plays a key role in the pathology...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-05-01
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| Series: | Pulmonary Circulation |
| Online Access: | https://doi.org/10.1177/2045894020922118 |