Ovarian gonadoblastoma with dysgerminoma in a girl with 46,XX karyotype 17a-hydroxylase/17, 20-lyase deficiency: A case report and literature review

Ovarian gonadoblastoma with dysgerminoma in a girl with 46,XX karyotype 17a-hydroxylase/17, 20-lyase deficiency: A case report and literature review

17α−hydroxylase/17,20−lyase deficiency (17-OHD), caused by mutations in the gene of the cytochrome P450 family 17 subfamily A member 1 (CYP17A1), is a rare type of congenital adrenal hyperplasia (CAH), usually characterized by cortisol and sex steroid deficiency combined with excessive mineralocorti...

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Bibliographic Details
Main Authors: Min Yin, Jiaxin Yang, Qinjie Tian, Xinyue Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
congenital adrenal hyperplasia
CYP17A1 gene
ovarian gonadoblastoma
dysgerminoma
17α-hydroxylase/17,20-lyase deficiency
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.989695/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.989695/full

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