Determinants of astrocytic pathology in stem cell models of primary tauopathies

Abstract Astrocytic tau aggregates are seen in several primary and secondary tauopathies, including progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and chronic traumatic encephalopathy (CTE). In all of these diseases, astrocytic tau consists mostly of the longer (4R) tau isofo...

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Bibliographic Details
Main Authors: Kimberly L. Fiock, Jordan N. Hook, Marco M. Hefti
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-023-01655-1