Myeloid-derived suppressor cells in multiple myeloma patients at the immune recovery and after high-dose chemotherapy and hematopoietic stem cell transplantation

Myeloid-derived suppressor cells in multiple myeloma patients at the immune recovery and after high-dose chemotherapy and hematopoietic stem cell transplantation

Introduction. Myeloid-derived suppressor cells (MDSCs) play an important role in restriction of the immune response and are associated with a poor prognosis in cancer. Mobilization of hematopoietic stem cells (HSCs) before high-dose chemotherapy (HCT) with autologous HSC transplantation (auto-HSCT)...

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Bibliographic Details
Main Authors: T. V. Tyrinova, E. V. Batorov, T. A. Aristova, G. Yu. Ushakova, S. A. Sizikova, V. V. Denisova, A. A. Ostanin, E. R. Chernykh
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2023-01-01
Series:Сибирский онкологический журнал
Subjects:
множественная миелома
трансплантация аутологичных гемопоэтических стволовых клеток
выживаемость до развития рецидива
супрессорные клетки миелоидного происхождения
супрессорные молекулы
аргиназа-1
г-ксф
Online Access:https://www.siboncoj.ru/jour/article/view/2372

Internet

https://www.siboncoj.ru/jour/article/view/2372

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