Effect of β-amyloid peptide 42 on the dynamics of expression and formation of Аβ(40), IL-1β, TNFα, IL-6, IL-10 by peripheral blood mononuclear cells in vitro and its correction by curcumin

The toxic effect of Аβ-oligomers accompanies chronic inflammation, with cytokines as main mediators. Therefore, the cytokine link of inflammation becomes a new target on the way to restrain amyloidosis. The aim of the study was the effect of aggregated Аβ42 on the dynamics of expression and formatio...

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Bibliographic Details
Main Authors: V. V. Sokolik, O. K. Koliada, S. M. Shulga
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2016-02-01
Series:The Ukrainian Biochemical Journal
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2016/03/Sokolik_1_16.pdf