Effect of β-amyloid peptide 42 on the dynamics of expression and formation of Аβ(40), IL-1β, TNFα, IL-6, IL-10 by peripheral blood mononuclear cells in vitro and its correction by curcumin
The toxic effect of Аβ-oligomers accompanies chronic inflammation, with cytokines as main mediators. Therefore, the cytokine link of inflammation becomes a new target on the way to restrain amyloidosis. The aim of the study was the effect of aggregated Аβ42 on the dynamics of expression and formatio...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2016-02-01
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Series: | The Ukrainian Biochemical Journal |
Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2016/03/Sokolik_1_16.pdf |