Genomic saturation mutagenesis and polygenic analysis identify novel yeast genes affecting ethyl acetate production, a non-selectable polygenic trait

Genomic saturation mutagenesis and polygenic analysis identify novel yeast genes affecting ethyl acetate production, a non-selectable polygenic trait

Isolation of mutants in populations of microorganisms has been a valuable tool in experimental genetics for decades. The main disadvantage, however, is the inability of isolating mutants in non-selectable polygenic traits. Most traits of organisms, however, are non-selectable and polygenic, includin...

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Bibliographic Details
Main Authors: Tom Den Abt, Ben Souffriau, Maria R. Foulquié-Moreno, Jorge Duitama, Johan M. Thevelein
Format: Article
Language:English
Published: Shared Science Publishers OG 2016-03-01
Series:Microbial Cell
Subjects:
Mutant screen
genomic mutagenesis
non-selectable trait
polygenic trait
QTL mapping
genetic basis
flavor production
ethyl acetate production
Online Access:http://microbialcell.com/researcharticles/genomic-saturation-mutagenesis-and-polygenic-analysis-identify-novel-yeast-genes-affecting-ethyl-acetate-production-a-non-selectable-polygenic-trait/

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http://microbialcell.com/researcharticles/genomic-saturation-mutagenesis-and-polygenic-analysis-identify-novel-yeast-genes-affecting-ethyl-acetate-production-a-non-selectable-polygenic-trait/

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