Gene-edited pigs: a translational model for human food allergy against alpha-Gal and anaphylaxis

Gene-edited pigs: a translational model for human food allergy against alpha-Gal and anaphylaxis

The prevalence of food allergy is rising and is estimated to approach 10%. Red meat allergy is the first known food allergy elicited by immunoglobulin E (IgE) antibodies recognizing a carbohydrate. Due to the loss of function of the alpha−1,3−galactosyltransferase (GGTA1) gene in humans, the disacch...

Full description

Bibliographic Details
Main Authors: Ying Wang, Miriam Hils, Andrea Fischer, Florian Wölbing, Tilo Biedermann, Angelika Schnieke, Konrad Fischer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
α-Gal allergy
anaphylaxis to α-Gal
intracutaneous sensitization
red meat allergy
translational pig model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1358178/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1358178/full

Similar Items