Design, Synthesis, and Antiproliferative Activity of Novel Neocryptolepine–Rhodanine Hybrids

Design, Synthesis, and Antiproliferative Activity of Novel Neocryptolepine–Rhodanine Hybrids

A series of novel neocryptolepine–rhodanine hybrids (<b>9a,b</b>, <b>11a</b>–<b>d</b>, <b>14</b>, and <b>16a,b</b>) have been synthesized by combining neocryptolepine core <b>5</b> modified at the C-11 position with rhodanine co...

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Bibliographic Details
Main Authors: Mohamed El-Bahnsawye, Mona K. Abo Hussein, Elshaymaa I. Elmongy, Hanem Mohamed Awad, Aliaa Abd El-Kader Tolan, Yasmine Shafik Moemen, Ahmed El-Shaarawy, Ibrahim El-Tantawy El-Sayed
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
neocryptolepine
alkaloids
rhodanine
hybrids
docking
pharmacokinetics
Online Access:https://www.mdpi.com/1420-3049/27/21/7599

Internet

https://www.mdpi.com/1420-3049/27/21/7599

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