Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability

Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability

Abstract Background The increasing use of gold nanoparticles (AuNPs) in the field of neuroscience instilled hope for their rapid translation to the clinical practice. AuNPs can be engineered to carry therapeutics or diagnostics in the diseased brain, possibly providing greater cell specificity and l...

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Bibliographic Details
Main Authors: Antonello Spinelli, Maria Girelli, Daniela Arosio, Laura Polito, Paola Podini, Gianvito Martino, Pierfausto Seneci, Luca Muzio, Andrea Menegon
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Nanobiotechnology
Subjects:
Gold nanoparticles
Intra cisterna magna
In vivo analysis
Online Access:http://link.springer.com/article/10.1186/s12951-019-0481-3

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http://link.springer.com/article/10.1186/s12951-019-0481-3

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