Activation of TLR-pathway to induce host Th1 immune response against visceral leishmaniasis: Involvement of galactosylated-flavonoids

Activation of TLR-pathway to induce host Th1 immune response against visceral leishmaniasis: Involvement of galactosylated-flavonoids

Immunotherapeutic strategies against visceral leishmaniasis (VL) are pertinent because of the emergence of resistance against existing chemotherapy, coupled with their toxicity and high costs. Various bioactive components with potential immunomodulatory activity, such as alkaloids, terpenes, saponin...

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Bibliographic Details
Main Authors: Supratim Pradhan, Snehlata, Debolina Manna, Subir Karmakar, Manoj Kumar Singh, Arijit Bhattacharya, Budhaditya Mukherjee, Joydeep Paul
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Heliyon
Subjects:
Antileishmanial
TLR-4
Galactosylated-Flavonoids
Reactive oxygen species
Th1 response
Visceral leishmaniasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022011562

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http://www.sciencedirect.com/science/article/pii/S2405844022011562

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