Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy.

Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy.

BACKGROUND: Glioblastoma is the most frequent and most malignant primary brain tumor with a poor prognosis. The translation of therapeutic strategies for glioblastoma from the experimental phase into the clinic has been limited by insufficient animal models, which lack important features of human tu...

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Bibliographic Details
Main Authors: Peter C Huszthy, Tsanan Giroglou, Oleg Tsinkalovsky, Philipp Euskirchen, Kai Ove Skaftnesmo, Rolf Bjerkvig, Dorothee von Laer, Hrvoje Miletic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2707627?pdf=render

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http://europepmc.org/articles/PMC2707627?pdf=render

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