Up-regulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosis.
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disorder characterized by fibroproliferation and excessive accumulation of extracellular matrix in the lung.Using oligonucleotide arrays, we identified osteopontin as one of the genes that significantly distinguishes IPF from normal lun...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2005-09-01
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| Series: | PLoS Medicine |
| Online Access: | http://europepmc.org/articles/PMC1198037?pdf=render |