Sex-Specific Modulation of the Host Transcriptome in the Spleen of Schistosoma mansoni-Infected Mice

BackgroundSchistosomiasis is a severe parasitic disease that is primarily driven by the host’s immune response to schistosome eggs trapped in tissue and by the granulomatous inflammatory and fibrotic reaction they cause. Despite significant progress in understanding the complex immunological process...

Full description

Bibliographic Details
Main Authors: Franziska Winkelmann, Anne Rabes, Cindy Reinholdt, Nicole Koslowski, Dirk Koczan, Emil C. Reisinger, Martina Sombetzki
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.893632/full