MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer

MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer

Abstract Background Aberrant activation of the Wnt/β-catenin signaling pathway is frequently observed in colorectal cancer (CRC). β-catenin is the major Wnt signaling pathway effector and inactivation of adenomatous polyposis coli (APC) results in nuclear accumulation of β-catenin. It has been sugge...

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Bibliographic Details
Main Authors: Ying Zhang, Lu Guo, Yuhuan Li, Gui-Hai Feng, Fei Teng, Wei Li, Qi Zhou
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Molecular Cancer
Subjects:
Colorectal cancer
microRNA
miR-494
Apc
Online Access:http://link.springer.com/article/10.1186/s12943-017-0753-1

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http://link.springer.com/article/10.1186/s12943-017-0753-1

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