Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata
The Janus kinase/signal transducers and activators of transcription (JAK/STAT) are key intracellular mediators in the signal transduction of many cytokines and growth factors. Common γ chain cytokines and interferon-γ that use the JAK/STAT pathway to induce biological responses have been implicated...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2021-04-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.142205 |