Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions.

The nucleus pulposus (NP) of the intervertebral disc functions to provide compressive load support in the spine, and contains cells that play a critical role in the generation and maintenance of this tissue. The NP cell population undergoes significant morphological and phenotypic changes during mat...

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Bibliographic Details
Main Authors: Christopher L Gilchrist, Eric M Darling, Jun Chen, Lori A Setton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3210142?pdf=render