The ATPase Inhibitory Factor 1 (IF1) Contributes to the Warburg Effect and Is Regulated by Its Phosphorylation in S39 by a Protein Kinase A-like Activity

The relevant role played by the ATPase Inhibitory Factor 1 (IF1) as a physiological in vivo inhibitor of mitochondrial ATP synthase in cancer and non-cancer cells, and in the mitochondria of different mouse tissues, as assessed in different genetic loss- and gain-of-function models of IF1 has been e...

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Bibliographic Details
Main Authors: José M. Cuezva, Sonia Domínguez-Zorita
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/5/1014