Dual inhibition of Wnt and Yes‐associated protein signaling retards the growth of triple‐negative breast cancer in both mesenchymal and epithelial states

Dual inhibition of Wnt and Yes‐associated protein signaling retards the growth of triple‐negative breast cancer in both mesenchymal and epithelial states

Triple‐negative breast cancer (TNBC), the most refractory subtype of breast cancer to current treatments, accounts disproportionately for the majority of breast cancer‐related deaths. This is largely due to cancer plasticity and the development of cancer stem cells (CSCs). Recently, distinct yet int...

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Bibliographic Details
Main Authors: Andrew Sulaiman, Sarah McGarry, Li Li, Deyong Jia, Sarah Ooi, Christina Addison, Jim Dimitroulakos, Angel Arnaout, Carolyn Nessim, Zemin Yao, Guang Ji, Haiyan Song, Suresh Gadde, Xuguang Li, Lisheng Wang
Format: Article
Language:English
Published: Wiley 2018-04-01
Series:Molecular Oncology
Subjects:
cancer stem cell
epithelial
mesenchymal
plasticity
triple‐negative breast cancer
Wnt
Online Access:https://doi.org/10.1002/1878-0261.12167

Internet

https://doi.org/10.1002/1878-0261.12167

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