Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells

<p>Abstract</p> <p>Background</p> <p>Folate (vitamin B9) is essential for cellular proliferation as it is involved in the biosynthesis of deoxythymidine monophosphate (dTMP) and s-adenosylmethionine (AdoMet). The link between folate depletion and the genesis and progres...

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Bibliographic Details
Main Authors: Matsui Sei-Ichi, VanDette Erika, Bistulfi Gaia, Smiraglia Dominic J
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/8/6