Increased HLA-G Expression in Term Placenta of Women with a History of Recurrent Miscarriage Despite Their Genetic Predisposition to Decreased HLA-G Levels

Increased HLA-G Expression in Term Placenta of Women with a History of Recurrent Miscarriage Despite Their Genetic Predisposition to Decreased HLA-G Levels

Human leukocyte antigen (HLA)-G is an immune modulating molecule that is present on fetal extravillous trophoblasts at the fetal-maternal interface. Single nucleotide polymorphisms (SNPs) in the 3 prime untranslated region (3&#8242;UTR) of the <i>HLA-G</i> gene can affect the level o...

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Bibliographic Details
Main Authors: Moniek H. C. Craenmehr, Iris Nederlof, Milo Cao, Jos J. M. Drabbels, Marijke J. Spruyt-Gerritse, Jacqueline D. H. Anholts, Hanneke M. Kapsenberg, Janine A. Stegehuis, Carin van der Keur, Esther Fasse, Geert W. Haasnoot, Marie-Louise P. van der Hoorn, Frans H. J. Claas, Sebastiaan Heidt, Michael Eikmans
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
HLA-G
immunohistochemistry
placenta
pregnancy
recurrent miscarriage
Online Access:https://www.mdpi.com/1422-0067/20/3/625

Internet

https://www.mdpi.com/1422-0067/20/3/625

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