Formulation and evaluation of co-prodrug of flurbiprofen and methocarbamol

The current work envisages synthesis of an ester prodrug of flurbiprofen whereby its carboxylic group was condensed with a skeletal muscle relaxant methocarbamol, with the aim of synergistic activity of two drugs, avoid flurbiprofen mediated gastro-intestinal damage and minimize the ulceration tende...

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Bibliographic Details
Main Authors: Neela Bhatia, Kiran Katkar, Snehal Ashtekar
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087615001312