Dysregulation of core neurodevelopmental pathways—a common feature of cancers with perineural invasion

Background: High nerve density in tumors and metastasis via nerves (perineural invasion—PNI) have been reported extensively in solid tumors throughout the body including pancreatic, head and neck, gastric, prostate, breast, and colorectal cancers. Ablation of tumor nerves results in improved disease...

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Bibliographic Details
Main Authors: Luz María González-Castrillón, Maud Wurmser, Daniel Öhlund, Sara Ivy Wilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1181775/full