PGM5-AS1 impairs miR-587-mediated GDF10 inhibition and abrogates progression of prostate cancer

PGM5-AS1 impairs miR-587-mediated GDF10 inhibition and abrogates progression of prostate cancer

Abstract Background Prostate cancer (PCa) is a leading cause of cancer-related death in males. Aberrant expression of long non-coding RNAs (lncRNAs) has been implicated in various human malignancies, including PCa. This study aims to clarify the inhibitory role of human PGM5 antisense RNA 1 (PGM5-AS...

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Bibliographic Details
Main Authors: Lei Du, Yongli Gao
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Translational Medicine
Subjects:
Prostate cancer
PGM5-AS1
MicroRNA-587
GDF10
Proliferation
Apoptosis
Online Access:https://doi.org/10.1186/s12967-020-02572-w

Internet

https://doi.org/10.1186/s12967-020-02572-w

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