Ursodeoxycholic Acid Treatment Restores Gut Microbiota and Alleviates Liver Inflammation in Non-Alcoholic Steatohepatitic Mouse Model

Ursodeoxycholic Acid Treatment Restores Gut Microbiota and Alleviates Liver Inflammation in Non-Alcoholic Steatohepatitic Mouse Model

Gut microbiota dysbiosis plays an important role in the progression of non-alcoholic fatty liver disease (NAFLD), and no approved drugs are available for NAFLD treatment. In this study, we aimed to explore the dynamic changes of gut microbiota at the different stages of NAFLD and determine whether u...

Full description

Bibliographic Details
Main Authors: Hu Li, Qingling Wang, Peizhan Chen, Chenghua Zhou, Xinxin Zhang, Li Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
non-alcoholic fatty liver disease
gastrointestinal microbiome
gut–liver axis
dysbiosis
therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.788558/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.788558/full

Similar Items