KLF5 promotes the ossification process of ligamentum flavum by transcriptionally activating CX43

KLF5 promotes the ossification process of ligamentum flavum by transcriptionally activating CX43

Abstract Background Ossification of ligamentum flavum (OLF) is a prevalent degenerative spinal disease, typically causing severe neurological dysfunction. Kruppel-like factor 5 (KLF5) plays an essential role in the regulation of skeletal development. However, the mechanism KLF5 plays in OLF remains...

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Bibliografiska uppgifter
Huvudupphovsmän: Hubing Guo, Lingxia Yang, Jin Liu, Liqi Chen, Yufeng Huang, Jinsong Li
Materialtyp: Artikel
Språk:English
Publicerad: BMC 2024-04-01
Serie:Journal of Orthopaedic Surgery and Research
Ämnen:
KLF5
Ligamentum flavum
Ossification
CX43
Länkar:https://doi.org/10.1186/s13018-024-04702-2

Internet

https://doi.org/10.1186/s13018-024-04702-2

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