CD4(+)CD62L(+) central memory T cells can be converted to Foxp3(+) T cells.

The peripheral Foxp3(+) Treg pool consists of naturally arising Treg (nTreg) and adaptive Treg cells (iTreg). It is well known that naive CD4(+) T cells can be readily converted to Foxp3(+) iTreg in vitro, and memory CD4(+) T cells are resistant to conversion. In this study, we investigated the indu...

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Bibliographic Details
Main Authors: Xiaolong Zhang, Xian Chang Li, Xiang Xiao, Rui Sun, Zhigang Tian, Haiming Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796486?pdf=render