Prediction of PPAR-α ligand-mediated physiological changes using gene expression profiles

Prediction of PPAR-α ligand-mediated physiological changes using gene expression profiles

Peroxisome proliferator-activated receptor (PPAR)-α controls the transcription of a variety of genes involved in lipid metabolism and is the target receptor for the hypolipidemic drug class of fibrates. In the present study, the molecular and physiological effects of seven different PPAR-activating...

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Bibliographic Details
Main Authors: Klaus Stensgaard Frederiksen, Erik Max Wulff, Per Sauerberg, John Patrick Mogensen, Lone Jeppesen, Jan Fleckner
Format: Article
Language:English
Published: Elsevier 2004-03-01
Series:Journal of Lipid Research
Subjects:
dyslipidemia
pharmacodynamics
peroxisome proliferator-activated receptor-α in vivo activation
transcriptional profiling
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318885

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http://www.sciencedirect.com/science/article/pii/S0022227520318885

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