Epigenome-Wide DNA Methylation Profiling in Colorectal Cancer and Normal Adjacent Colon Using Infinium Human Methylation 450K

Epigenome-Wide DNA Methylation Profiling in Colorectal Cancer and Normal Adjacent Colon Using Infinium Human Methylation 450K

The aims were to profile the DNA methylation in colorectal cancer (CRC) and to explore cancer-specific methylation biomarkers. Fifty-four pairs of CRCs and the adjacent normal tissues were subjected to Infinium Human Methylation 450K assay and analysed using ChAMP R package. A total of 26,093 differ...

Full description

Bibliographic Details
Main Authors: Rashidah Baharudin, Muhiddin Ishak, Azliana Muhamad Yusof, Sazuita Saidin, Saiful Effendi Syafruddin, Wan Fahmi Wan Mohamad Nazarie, Learn-Han Lee, Nurul-Syakima Ab Mutalib
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Diagnostics
Subjects:
colorectal cancer
DNA methylation
adjacent normal colon
Infinium Human Methylation 450K
microarray
Online Access:https://www.mdpi.com/2075-4418/12/1/198

Internet

https://www.mdpi.com/2075-4418/12/1/198

Similar Items