Red and golden tomato administration improves fat diet-induced hepatic steatosis in rats by modulating HNF4α, Lepr, and GK expression

Red and golden tomato administration improves fat diet-induced hepatic steatosis in rats by modulating HNF4α, Lepr, and GK expression

IntroductionNonalcoholic fatty liver disease (NAFLD), characterized by lipid accumulation within hepatocytes exceeding 5% of liver weight, is strongly related to metabolic disorders, obesity, and diabetes and represents a health emergency worldwide. There is no standard therapy available for NAFLD....

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Main Authors: Rosaria Maria Pipitone, Rossella Zito, Giuditta Gambino, Gabriele Di Maria, Ayesha Javed, Giulia Lupo, Giuseppe Giglia, Pierangelo Sardo, Giuseppe Ferraro, Francesca Rappa, Daniela Carlisi, Danila Di Majo, Stefania Grimaudo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Nutrition
Subjects:
nonalcoholic fatty liver disease
golden tomato
red tomato
LEPR
NFH4a
GK
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1221013/full

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https://www.frontiersin.org/articles/10.3389/fnut.2023.1221013/full

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