LncRNA <i>H19</i>-Derived <i>miR-675-5p</i> Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting <i>GATA2</i> and Subsequently Activating Matrix Metalloproteinases

LncRNA <i>H19</i>-Derived <i>miR-675-5p</i> Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting <i>GATA2</i> and Subsequently Activating Matrix Metalloproteinases

The invasion of extravillous trophoblast (EVT) cells into the maternal decidua, which plays a crucial role in the establishment of a successful pregnancy, is highly orchestrated by a complex array of regulatory mechanisms. Non-coding RNAs (ncRNAs) that fine-tune gene expression at epigenetic, transc...

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Bibliographic Details
Main Authors: Manabu Ogoyama, Akihide Ohkuchi, Hironori Takahashi, Dongwei Zhao, Shigeki Matsubara, Toshihiro Takizawa
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
extravillous trophoblast
cell invasion
long non-coding RNA <i>H19</i>
<i>miR-675-5p</i>
GATA2
matrix metalloproteinase
Online Access:https://www.mdpi.com/1422-0067/22/3/1237

Internet

https://www.mdpi.com/1422-0067/22/3/1237

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