The esBAF and ISWI nucleosome remodeling complexes influence occupancy of overlapping dinucleosomes and fragile nucleosomes in murine embryonic stem cells

Abstract Background Nucleosome remodeling factors regulate the occupancy and positioning of nucleosomes genome-wide through ATP-driven DNA translocation. While many nucleosomes are consistently well-positioned, some nucleosomes and alternative nucleosome structures are more sensitive to nuclease dig...

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Bibliographic Details
Main Authors: David C. Klein, Kris Troy, Sarah A. Tripplehorn, Sarah J. Hainer
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-023-09287-4