Bioanalytical Method Validation of Metformin Hydrochloride in Human Plasma by HPLC-UV for Preliminary Population-Based Pharmacokinetic Modeling Study

Bioanalytical Method Validation of Metformin Hydrochloride in Human Plasma by HPLC-UV for Preliminary Population-Based Pharmacokinetic Modeling Study

This study aims to validate the method for measuring metformin hydrochloride plasma concentrations using High-Performance Liquid Chromatography (HPLC). This research performed chromatography on a 250 mm 4.6 mm 5 µm purosphere® Star RP-18 column at ambient temperature with a UV detector system at 233...

Full description

Bibliographic Details
Main Authors: Dimas Adhi Pradana, Erna Kristin, Akhmad Kharis Nugroho, Dwi Aris Agung Nugrahaningsih, Mustofa Mustofa, Ari Wibowo
Format: Article
Language:English
Published: Department of Chemistry, Universitas Gadjah Mada 2023-08-01
Series:Indonesian Journal of Chemistry
Subjects:
human plasma
hplc-uv
metformin hcl
pharmacokinetic
validation
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/77903

Internet

https://jurnal.ugm.ac.id/ijc/article/view/77903

Similar Items