Mouse serum albumin induces neuronal apoptosis and tauopathies

Mouse serum albumin induces neuronal apoptosis and tauopathies

Abstract The elderly frequently present impaired blood–brain barrier which is closely associated with various neurodegenerative diseases. However, how the albumin, the most abundant protein in the plasma, leaking through the disrupted BBB, contributes to the neuropathology remains poorly understood....

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Bibliographic Details
Main Authors: Sheng-jie Hou, Ya-ru Huang, Jie Zhu, Ying-bo Jia, Xiao-yun Niu, Jin-ju Yang, Xiao-lin Yu, Xiao-yu Du, Shi-yu Liang, Fang Cui, Ling-jie Li, Chen Tian, Rui-tian Liu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Acta Neuropathologica Communications
Subjects:
Mouse serum albumin
Neuroinflammation
Apoptosis
Tau phosphorylation
Online Access:https://doi.org/10.1186/s40478-024-01771-6

Internet

https://doi.org/10.1186/s40478-024-01771-6

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