Structure of an Intranucleosomal DNA Loop That Senses DNA Damage during Transcription

Structure of an Intranucleosomal DNA Loop That Senses DNA Damage during Transcription

Transcription through chromatin by RNA polymerase II (Pol II) is accompanied by the formation of small intranucleosomal DNA loops containing the enzyme (i-loops) that are involved in survival of core histones on the DNA and arrest of Pol II during the transcription of damaged DNA. However, the struc...

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Bibliographic Details
Main Authors: Nadezhda S. Gerasimova, Olesya I. Volokh, Nikolay A. Pestov, Grigory A. Armeev, Mikhail P. Kirpichnikov, Alexey K. Shaytan, Olga S. Sokolova, Vasily M. Studitsky
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
nucleosome
transcription
RNA polymerase II
elongation complex
structure
DNA damage
Online Access:https://www.mdpi.com/2073-4409/11/17/2678

Internet

https://www.mdpi.com/2073-4409/11/17/2678

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