Quantifying the interplay between genetic and epigenetic regulations in stem cell development

Waddington epigenetic landscape, as a classic metaphor, has been used to explain cellular development and differentiation. However, it remains challenging to quantify the epigenetic landscape. Especially, a key issue arises as what are the underlying mechanisms for the interplay between genetic and...

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Bibliographic Details
Main Authors: Yunbin Zhang, Ning Liu, Wei Lin, Chunhe Li
Format: Article
Language:English
Published: IOP Publishing 2019-01-01
Series:New Journal of Physics
Subjects:
Online Access:https://doi.org/10.1088/1367-2630/ab4c82