Quantifying the interplay between genetic and epigenetic regulations in stem cell development
Waddington epigenetic landscape, as a classic metaphor, has been used to explain cellular development and differentiation. However, it remains challenging to quantify the epigenetic landscape. Especially, a key issue arises as what are the underlying mechanisms for the interplay between genetic and...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
IOP Publishing
2019-01-01
|
Series: | New Journal of Physics |
Subjects: | |
Online Access: | https://doi.org/10.1088/1367-2630/ab4c82 |