Increased prevalence of clonal hematopoiesis of indeterminate potential in hospitalized patients with COVID-19

Increased prevalence of clonal hematopoiesis of indeterminate potential in hospitalized patients with COVID-19

Clonal hematopoiesis of indeterminate potential (CHIP) leads to higher mortality, carries a cardiovascular risk and alters inflammation. All three aspects harbor overlaps with the clinical manifestation of COVID-19. This study aimed to identify the impact of CHIP on COVID-19 pathophysiology. 90 hosp...

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Bibliographic Details
Main Authors: Judith Schenz, Katharina Rump, Benedikt Hermann Siegler, Inga Hemmerling, Tim Rahmel, Jan N. Thon, Hartmuth Nowak, Dania Fischer, Anna Hafner, Lucas Tichy, Katharina Bomans, Manja Meggendorfer, Björn Koos, Thilo von Groote, Alexander Zarbock, Mascha O. Fiedler, Johanna Zemva, Jan Larmann, Uta Merle, Michael Adamzik, Carsten Müller-Tidow, Torsten Haferlach, Florian Leuschner, Markus A. Weigand
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
cardiac function
CHIP
critically ill
immune system
SARS-CoV-2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.968778/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.968778/full

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