Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm

Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm

Implant-associated Staphylococcus aureus infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. Monoclonal antibodies (mAbs) could provide an alternative approach to improve the diagnosis and potential treatment o...

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Bibliographic Details
Main Authors: Lisanne de Vor, Bruce van Dijk, Kok van Kessel, Jeffrey S Kavanaugh, Carla de Haas, Piet C Aerts, Marco C Viveen, Edwin C Boel, Ad C Fluit, Jakub M Kwiecinski, Gerard C Krijger, Ruud M Ramakers, Freek J Beekman, Ekaterina Dadachova, Marnix GEH Lam, H Charles Vogely, Bart CH van der Wal, Jos AG van Strijp, Alexander R Horswill, Harrie Weinans, Suzan HM Rooijakkers
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
Staphylococcus aureus
biofilm
monoclonal antibodies
Online Access:https://elifesciences.org/articles/67301

Internet

https://elifesciences.org/articles/67301

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