Hearing Impairment in a Mouse Model of Diabetes Is Associated with Mitochondrial Dysfunction, Synaptopathy, and Activation of the Intrinsic Apoptosis Pathway

Hearing Impairment in a Mouse Model of Diabetes Is Associated with Mitochondrial Dysfunction, Synaptopathy, and Activation of the Intrinsic Apoptosis Pathway

Although previous studies continuously report an increased risk of hearing loss in diabetes patients, the impact of the disease on the inner ear remains unexplored. Herein, we examine the pathophysiology of diabetes-associated hearing impairment and cochlear synaptopathy in a mouse model of diabetes...

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Bibliographic Details
Main Authors: Ah-Ra Lyu, Tae-Hwan Kim, Sun-Ae Shin, Eung-Hyub Kim, Yang Yu, Akanksha Gajbhiye, Hyuk-Chan Kwon, A Reum Je, Yang Hoon Huh, Min Jung Park, Yong-Ho Park
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
cochlear mitochondria
microangiopathy
synaptopathy
sensory loss
apoptosis
necroptosis
Online Access:https://www.mdpi.com/1422-0067/22/16/8807

Internet

https://www.mdpi.com/1422-0067/22/16/8807

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