Next-generation version of recombinant human interferon-beta: A molecular dynamic simulation study

Next-generation version of recombinant human interferon-beta: A molecular dynamic simulation study

The ability of recombinant human interferon beta-1b (IFNβ-1b) to elicit the production of anti-IFNβ-1b antibodies becomes a significant issue for interferon therapy in patients. Mitigating the immunogenicity issues requires understanding the stimulating factors in observed immune responses. Among mu...

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Bibliographic Details
Main Authors: Mohadeseh Haji Abdolvahab, Rayeheh Vafaee, S. Shahriar Arab, Mehrdad Behmanesh
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Interferon-beta
Epitope
Variant protein
Immunogenicity
MHC class II
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914822001782

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http://www.sciencedirect.com/science/article/pii/S2352914822001782

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