Cancer-Associated Fibroblasts Exposed to High-Dose Ionizing Radiation Promote M2 Polarization of Macrophages, Which Induce Radiosensitivity in Cervical Cancer

Cancer-Associated Fibroblasts Exposed to High-Dose Ionizing Radiation Promote M2 Polarization of Macrophages, Which Induce Radiosensitivity in Cervical Cancer

Radiotherapy, including brachytherapy, is a major therapeutic regimen for cervical cancer. Radioresistance is a decisive factor in radiation treatment failure. Tumor-associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs) in the tumor microenvironment are critical factors in the curat...

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Bibliographic Details
Main Authors: Yuhan Sheng, Baofang Zhang, Biyuan Xing, Zhao Liu, Yu Chang, Gang Wu, Yingchao Zhao
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
cervical cancer
radiotherapy
radioresistance
tumor-associated macrophages
cancer-associated fibroblasts
Online Access:https://www.mdpi.com/2072-6694/15/5/1620

Internet

https://www.mdpi.com/2072-6694/15/5/1620

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