Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection
Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary tract infections. However, the dynamic responses of IBCs to host stresses and antibiotic therapy are difficult to assess in si...
Main Authors: | Kunal Sharma, Neeraj Dhar, Vivek V Thacker, Thomas M Simonet, Francois Signorino-Gelo, Graham W Knott, John D McKinney |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/66481 |
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