CK2 Phosphorylation Is Required for Regulation of Syntaxin 1A Activity in Ca<sup>2+</sup>-Triggered Release in Neuroendocrine Cells
The polybasic juxtamembrane region (5RK) of the plasma membrane neuronal SNARE, syntaxin1A (Syx), was previously shown by us to act as a fusion clamp in PC12 cells, as charge neutralization of 5RK promotes spontaneous and inhibits Ca<sup>2+</sup>-triggered release. Using a Syx-based FRET...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-12-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/24/13556 |